We detect neuroinflammation biomarkers to decide which drug candidate moves forward.

Reproducible, longitudinal pharmacological profiles for CNS drug discovery.

US$ 27.6B

CNS drug discovery market by 2035

11%

Annual growth (CAGR) 2025-2035

An aging population and regulation that favors human-relevant models.

Precedence Research

Almost no Alzheimer's drug makes it to approval.

98%

Phase II/III failure rate in Alzheimer's over the last two decades

Kim et al., 2022

US$ 1.3B

Average cost to bring a drug to market

Wouters et al., 2020

US$ 250M/yr

Spent on failing anti-neuroinflammatory trials

Kim, 2022; Cummings et al., 2025

From cellular response to pharmacological profile.

  1. 3D neuroglial model

    Astrocytes and microglia in 3D.

  2. Controlled perturbation

    Compound or inflammatory challenge.

  3. Longitudinal monitoring

    Specific biomarkers, tracked over time.

  4. Auditable profile

    Data for go/no-go decisions.

Our science is published, and regulation is moving our way.

Peer-reviewed Frontiers in Pharmacology | 2021

Pathological neuroinflammatory conversion of reactive astrocytes is induced by microglia and involves chromatin remodeling.

Villarreal A. et al.

Read the paper
Regulation FDA | 2022

FDA Modernization Act 2.0

Opens the door to human-relevant alternatives to animal testing.

From analytical service to data platform.

Pilot studies

Fee-for-service validation.

Recurring screening

Annual batch contracts.

Co-development

Custom, milestone-based.

Data & licensing

Proprietary database access.

Biology to decode the brain. Engineering to put it on a chip.

Javier Amado

Javier Amado

Co-founder | Microfluidics

Ex Stämm Biotech2 patents
LinkedIn
Alejandro Villarreal

Alejandro Villarreal

Neuroinflammation

PhD | H-index 19
LinkedIn
Gastón Corti

Gastón Corti

Devices & manufacturing

Ex Stämm Biotech1 patent
LinkedIn
Carolina Silveri

Carolina Silveri

Molecular biology

Bioengineering
LinkedIn
Victoria Mau

Victoria Mau

Engineering & development

Bioengineering
LinkedIn
The NiC team at Crossing Over 2026
Crossing Over 2026 | LATAM BioExpo | Buenos Aires

Want to learn more about our technology?

Talk directly with the founders.